Nematode pathogens threaten livestock production and global food security.  Resistance-induced inefficacy is common amongst many of the current anti-nematode therapeutics and will render them obsolete in the not-so-distant future.  Sustained nematode pathogen control relies on the delivery of novel chemotherapeutics and/or development of resistance-breaking control strategies, and requires new/improved drug discovery tools.

My research focusses on the identification and priortisation of novel control targets within the neuropeptidergic system of nematodes, and the development of functional genomics platforms for control-target validation.