Nanomedicine and Biotherapeutics
Development of novel technologies and targeted therapies for advanced healthcare solutions.
Research in this theme is focused on the development of novel technologies and targeted therapies for advanced healthcare solutions. Activities are concentrated on the development of unique genetic therapies and delivery systems that can be applied for the detection and treatment of cancer, the development of novel strategies for the detection, characterisation and inhibition of proteases implicated in chronic diseases, the isolation and characterisation of bioactive peptides for potential therapeutic use and computational biology for drug design and molecular modelling.
Research Theme Leads
Professor Jonathan Coulter
Email: j.coulter@qub.ac.uk
Dr Fiona Furlong
Email: f.furlong@qub.ac.uk
Research themes and areas of activity
Anticancer therapeutics
Research activities are focussed on a greater understanding of the molecular interactions and development of unique genetic therapies that can be applied for the detection and treatment of highly aggressive metastatic disease.
Nano-delivery of macromolecules
Research activities are focussed on the design and synthesis of nanotechnologies as local and systemic delivery systems for DNA, RNAi, miRNA, and Au nanoparticle therapies.
Proteases in Disease
Research activities are focussed on the development of novel strategies for the detection, characterisation and inhibition of proteases implicated in chronic diseases including respiratory, cardiovascular, cancer and infection with an emphasis on ion channel modulation, inflammatory microenvironments and immune signalling.
Natural Peptides
Research activities are focussed on the isolation and characterisation of bioactive peptides derived from animal venoms in order to discover novel antimicrobial, anticancer, antidiabetic, antihypertensive and immunostimulating therapeutic agents.
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