Multi-omic factors that influence human disease, particularly kidney disease. Our laboratories are well-equipped, including high-density array scanners and next generation sequencing machines. Her team are building the NICOLA bioresource with a focus on older individuals. Whole genome sequencing rare diseases is underway as part of the NI Genomic Medicine Centre with the complementary development of an online information hub and patient-centred pathways. We hold several registries and are actively engaged in making maximal use of complex genomic information.